The gut microbiota is shaped and regulated by multiple factors including our genomic composition, the local intestinal niche and multiple environmental factors including our nutritional repertoire and bio-geographical location. Dysregulation of these genetic or environmental factors leads to aberrant host-microbiome interactions, ultimately predisposing to pathologies ranging from chronic inflammation, obesity, the metabolic syndrome and even cancer.
This year’s Crohn’s & Colitis Congress keynote address is by Dr. Elinav, professor at the Department of Immunology, Weizmann Institute of Science, in Israel, and his topic is Host Microbiome Interactions in Health and Disease. His talk will revolve around his lab’s work in decoding the molecular basis of host-microbiome interactions, with an aim to understand how these interactions impact gut hoeostasis, and the risk of developing a variety of disorders, ranging from inflammatory bowel disease (IBD), metabolic disorders, cancer and more.
Dr. Elinav’s lab has identified various possible mechanisms participating in the reciprocal regulation between the host and the intestinal microbial ecosystem, and demonstrates that disruption of these factors, in mice and humans, lead to dysbiosis and susceptibility to common multi-factorial disease.
You can hear Dr. Elinav’s keynote address at the Crohn’s & Colitis Congress, taking place Feb. 7-9, 2019, at the Bellagio Las Vegas. The Crohn’s & Colitis Congress is the premier conference on IBD and is a partnership of the Crohn’s & Colitis Foundation and AGA. It provides a multidisciplinary perspective on treating IBD for health care professionals and researchers. To learn more and register, visit www.crohnscolitiscongress.org.