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AGA to FDA: We support new labeling recommendations for probiotics

In a new comment letter to FDA, AGA commends FDA’s recent draft guidance — “Policy Regarding Quantitative Labeling of Dietary Supplements Containing Live Microbials” — clarifying the expectations of probiotics manufacturers who choose to specify the amount of a live microbial component in their product in colony forming units (CFUs). Though manufacturers are not currently required […]

Making Sense of Pre-, Pro- and Synbiotics

By Purna Kashyap, MBBS, scientific advisory board member, AGA Center for Gut Microbiome Research and Education   Probiotics are live microorganisms that, when given in sufficient amounts, are expected to confer a health benefit on the host. In general, probiotics have been shown to have beneficial effects on human health in a range of […]

Reality check on microbiome science

[…] from the probiotic product colonizing in the guts of some individuals but not others. These results were preliminary but exciting, and led to headlines ranging from “ Probiotics’ effects on the microbiome vary widely” to “Probiotics labeled ‘quite useless’.” Readers who did not continue past the headline could draw quite different conclusions depending on […]

Prebiotics 101

[…] in diverse body sites, and non-food applications.4  The earliest prebiotic products were intended to increase colonic populations of Bifidobacterium and Lactobacillus5 — the first organisms designated “ probiotics” as defined by the World Health Organization (WHO).6 These bacteria produce strong acids (lactate and acetate), digestive enzymes, and cofactors, and displayed early evidence of immunomodulatory behavior.2 Initially, […]

GUT Microbiota Dysbiosis

The Gut Microbiota Decade: A Major Discovery That Will Shape the Future of Medical Practice

[…] microbiota,” points out Dr. Liping Zhao, professor of microbiology at Shanghai Jiao Tong University and leader of the Functional Metagenomics Platform at Shanghai Center for Systems Biomedicine.  Probiotics have been tested in many clinical trials to date. Some of them demonstrated benefits of probiotics in prevention of antibiotic-associated diarrhea, of allergy disease in early life, […]

Role of probiotics in the management of gastrointestinal disorders

Role of probiotics in the management of gastrointestinal disorders

Find out if probiotics are recommended, and if so what strains, for specific GI conditions. This guideline covers C. difficile infection, adults and children on antibiotic treatment, Crohn’s disease, ulcerative colitis, pouchitis, irritable bowel syndrome (IBS), acute infectious gastroenteritis, and preterm/low-birth-weight infants.

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