AGA Family of Websites: Gastro.org

Expert tips for diagnosing and treating sclerosing mesenteritis

Symptomatic cases present abdominal pain that corresponds to lesions seen on imaging.
Sclerosing mesenteritis
Sclerosing mesenteritis

A new AGA clinical practice update (CPU) focuses on sclerosing mesenteritis, a rare and poorly understood disorder of bowel mesentery characterized by inflammation, fat necrosis, and fibrosis. The update offers guidance on diagnosing and treating the condition and a roadmap for future research.

Key takeaway:

While most cases are asymptomatic and don’t require treatment, symptomatic cases present abdominal pain that corresponds to lesions seen on imaging. These are typically managed with anti-inflammatory medications. More severe cases may require referral to a specialist.

In the CPU, experts emphasize the need to better understand the underlying inflammatory mechanisms, including the role of cytokines and other mediators, to develop more targeted therapies with fewer side effects and quicker clinical responses.

Watch as Drs. Mark Worthington and Seth Crockett discuss the prevalence and diagnostic criteria for sclerosing mesenteritis.

Read more in the full AGA CPU published in the May issue of Clinical Gastroenterology and Hepatology.

Stay in the know with AGA

Members receive our weekly newsletter, AGA eDigest, which is packed with clinical education updates, career development opportunities, member news and more.

Stay connected. Stay informed. Stay ahead.

AGA clinical guidance

Find the latest evidence-based recommendations for treating your patients.

X
American Gastroenterological Association
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.