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Guideline

Management of Crohn’s disease after surgical resection

Strategies to reduce disease recurrence in Crohn's disease patients who have achieved remission following bowel resection.
Find the latest clinical guidance, education, patient resources and more in our Crohn's disease toolkit.

Guideline Tool kits

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Recommendations

1. In patients with surgically induced remission of Crohn’s disease, AGA suggests early pharmacological prophylaxis over endoscopy-guided pharmacological treatment.

2. In patients with surgically induced remission of Crohn’s disease, AGA suggests using anti-tumor necrosis factor (anti-TNF) therapy and/or thiopurines over other agents.

3. In patients with surgically induced remission of Crohn’s disease, AGA suggests against using mesalamine (or other 5-aminosalicylates), budesonide or probiotics.

4. In patients with surgically induced remission of Crohn’s disease receiving pharmacological prophylaxis, AGA suggests postoperative endoscopic monitoring at 6 to 12 months after surgical resection over no monitoring.

5. In patients with surgically induced remission of Crohn’s disease not receiving pharmacological prophylaxis, AGA recommends postoperative endoscopic monitoring at 6 to 12 months after surgical resection over no monitoring.

6. In patients with surgically induced remission of Crohn’s disease with asymptomatic endoscopic recurrence, AGA suggests initiating or optimizing anti-TNF and/or thiopurine therapy over continued monitoring alone.

Resources

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