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Clinical Guidelines

AGA’s clinical guidelines are evidence-based recommendations to help guide your clinical practice decisions based on rigorous systematic reviews of the medical literature. AGA utilizes the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. Learn more about GRADE
Our guidelines are regularly reviewed for accuracy, relevance, and clinical impact. AGA endorses guidelines that meet the National Academy of Medicine’s rigorous criteria for evidence-based clinical recommendations. 
AGA is dedicated to transparency in the development of clinical guidelines. Read our statement on the integrity of AGA’s clinical guideline process.

Upcoming Guidelines

Use of Pharmacological Therapies in the Treatment of IBS - Update

Fall 2021/Winter 2022

Coagulation in Cirrhosis

Fall 2021/Winter 2022

Systemic Therapy for HCC

Winter 2022

Use of Pharmacological Therapies in the Treatment of IBS


This guideline will address the following clinical questions such as:

  • What new pharmacologic agents for the treatment of IBS that have become available and new evidence that has accumulated about selected treatments since the original publication of the IBS guidelines in 2014?
  • What is the effect of various pharmacologic interventions on patient-important outcomes?

The GI Evaluation of Iron Deficiency Anemia


This guideline will address the use of gastrointestinal evaluation to identify the source of iron deficiency anemia and promote its resolution in patients, such as:

  • Recommended types of endoscopy to perform (e.g., capsule endoscopy, push enteroscopy, enterocyclis).
  • Recommended intervals and context for repeated endoscopy.
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