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Eosinophilic esophagitis (EoE) toolkit

Clinician's toolkit

Eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is an illness found in the esophagus that is the result of an allergy to certain foods or something else in the environment. 

It occurs when a type of white blood cell, the eosinophil, builds up in the esophagus, causing irritation and scarring. Some patients with EoE will also have other areas of the digestive tract affected with increased eosinophils, including the stomach, small intestine and large intestine (colon). This is rare but more likely in children. 

EoE may cause trouble swallowing, heartburn and food getting stuck in the throat. Infants, children and adults can all have EoE. It is a lifelong health issue. 

For physicians

I-SEE tool

Over the past three decades, EoE has transformed from a little-known condition to a well-characterized disease often encountered in clinical practice. In light of this, AGA convened a multidisciplinary team of experts who created a tool to grade the severity of EoE using an array of clinicopathologic criteria. The Index of Severity for EoE (I-SEE) allows you to assess and track EoE activity for your patients in an impactful way.

The I-SEE tool is available as an iOS and Android app!

Additional clinical guidance for physicians

Recommendations for allergists and gastroenterologists focusing on the clinical management of eosinophilic esophagitis (EoE) for pediatric and adult patients.

This review aims to summarize evidence in support of dietary therapy while providing guidance on initiation and implementation of dietary therapy for providers.

For physicians

Education

AGA University helps physicians learn about how to care for people with eosinophilic esophagitis – including understanding disease progression and treatments 

For patients

Patient resources

AGA’s GI Patient Center can help your patients understand eosinophilic esophagitis: symptoms, tests, treatments, complications. The EoE Patient Resource Center provides additional resources for caregivers, teens, and adults.

For patients

Eosinophilic esophagitis FAQs

Learn more about eosinophilic esophagitis (EoE), symptoms, testing and treatment below.

Eosinophilic esophagitis (EoE) is an illness found in the esophagus, which is caused by an allergy to certain foods (which are not the same for all people).

EoE affects people of all ages and ethnic backgrounds. The condition is estimated to occur in 1 out of 1,700 people.

Symptoms of EoE are not the same from one person to the next. Some common symptoms for adults include trouble swallowing, heartburn, upset stomach or vomiting.

Finding out you have EoE can only be done by an endoscopy and taking small tissue samples of the esophagus (the tube that links your mouth and stomach).

The three main choices to care for your eosinophilic esophagitis are changes to your diet, using certain medications, and esophageal dilation. 

Along with your GI doctor, you also need to see an allergist and expert registered dietitian (RD) for this condition. Your GI doctor, allergist and RD will talk with you about which choices are best for your case. Learn more about treatment options. 

There are a few diet options that may help you care for your EoE, including targeted elimination diet, six-food elimination diet, elemental diet and food trials. Learn more.

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